Paper Titles
Surface Modification of Nanosized Biphasic α-TCP/HA Powders
p.223
Surface Dissolution of Hydroxyapatite Prepared by Microwave Sintering
p.227
Synthesis and Dispersion of Magnetic Nano-Particles by a Surfactant-Mediated Approach
p.231
Preparation and Characterization of Nano Hydroxyapatite
p.235
Synthesis of Albumin/DCP Nano-Composite Particles
p.239
Microspheres Based on Hydroxyapatite Nanoparticles Aggregates for Bone Regeneration
p.243
Hydrothermal Synthesis of Nano-Crystalline Hydroxyapatite
p.247
Caries Inhibitory Activity of the Nano-HA In Vitro
p.251
Structural Properties of Hydroxyapatite With Particle Size Less Than 10 Nanometers
p.255

Synthesis of Albumin/DCP Nano-Composite Particles

Article Preview

Abstract:

Highly disgregated dicalcium phosphate anhydrate (DCP) nanoparticles 240-367 nm in diameter were synthesized by a reaction between calcium carbonate and phosphoric acid. When the DCP nanoparticles were immersed in a supersaturated calcium phosphate solution containing bovine serum albumin (BSA) and ethanol, BSA/DCP nano-composite particles were synthesized through the coprecipitation of BSA on the DCP nanoparticles. BSA was firmly immobilized on the BSA/DCP nano-composite particles. The results of this study suggest that DCP nanoparticles appear to be useful as a drug delivery vehicle.

You might also be interested in these eBooks
Bioceramics 19 View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

239-242

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.239

Citation:

Cite this paper

Online since:

February 2007

Authors:

Hajime Ohsawa, Atsuo Ito, Yu Sogo, Atsushi Yamazaki, Tadao Ohno

Keywords:

Bovine Serum Albumin (BSA), Coprecipitation, Dicalcium Phosphate Anhydrate, Drug Delivery Vehicle, Nanoparticle

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2007 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] T. Matsumoto, M. Okazaki, M. Inoue, S. Yamaguchi, T. Kusunose, T. Toyonaga, Y. Hamada, J. Takahashi: Biomaterials, Vol. 25(2004), p.3807.

DOI: 10.1016/j.biomaterials.2003.10.081

Google Scholar

[2] W. Paul, J. Nesamony, C. P. Sharma: J. Biomed. Mater. Res. Vol. 61(2002), p.660.

Google Scholar

[3] K. Inoue, K. Sassa, Y. Yokogawa, Y. Sakka, M. Okido and S. Asai: Bioceramics, Vol. 15(2002), p.513.

Google Scholar

[4] Fujii O, Ito A, Otsuka R, Aoki H, Akao M: Gypsum and Lime 219, (1989) p.68 (Japanese).

Google Scholar

[5] Y. Sogo, A. Ito, K. Fukasawa et al: Curr Appl Phys Vol. 5(2005), p.526.

Google Scholar

[6] M. Uchida, A. Oyane et al.: Adv. Mater., Vol. 16(2004), p.1071.

Google Scholar

[7] A. Oyane, M. Uchida and A. Ito: J. Biomed. Mater. Res., Vol. 72A(2005).

Google Scholar