Paper Titles
Surface Dissolution of Hydroxyapatite Prepared by Microwave Sintering
p.227
Synthesis and Dispersion of Magnetic Nano-Particles by a Surfactant-Mediated Approach
p.231
Preparation and Characterization of Nano Hydroxyapatite
p.235
Synthesis of Albumin/DCP Nano-Composite Particles
p.239
Microspheres Based on Hydroxyapatite Nanoparticles Aggregates for Bone Regeneration
p.243
Hydrothermal Synthesis of Nano-Crystalline Hydroxyapatite
p.247
Caries Inhibitory Activity of the Nano-HA In Vitro
p.251
Structural Properties of Hydroxyapatite With Particle Size Less Than 10 Nanometers
p.255
Sintering Behaviour of Nanosized HAP Powder
p.259

Microspheres Based on Hydroxyapatite Nanoparticles Aggregates for Bone Regeneration

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Abstract:

This study concerns the preparation and characterisation of microspheres associating alginate and two different types of hydroxyapatite (HA), which are intended to be used as drug delivery systems and bone regeneration matrices. Hydroxyapatite nanoparticles (HA-1 and HA-2) were prepared using a chemical precipitation synthesis based on H3PO4, Ca(OH)2 and a surfactant, SDS (sodium dodecylsulphate), as starting reagents. These two powders of nanoHA and alginate were used to prepare two different types of microspheres. Both powders and microspheres were characterised using FTIR, TEM, SEM, mercury porosimetry analysis and X-ray diffraction Results show that pure hydroxyapatite (HA) and mixtures of HA/β-TCP in the nanometre range were obtained from both HA syntheses. Microspheres with different characteristics were obtained from these two types of hydroxyapatite.

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Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

243-246

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.243

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Online since:

February 2007

Authors:

A. Yovana Pataquiva Mateus, M.P. Ferraz, F.J. Monteiro

Keywords:

Alginate, Bone Regeneration, Chemical Precipitation, Hydroxyapatite (HAP), Micro-Sphere, Nanoparticle

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© 2007 Trans Tech Publications Ltd. All Rights Reserved

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