Paper Titles
Preparation and Characterization of Nano Hydroxyapatite
p.235
Synthesis of Albumin/DCP Nano-Composite Particles
p.239
Microspheres Based on Hydroxyapatite Nanoparticles Aggregates for Bone Regeneration
p.243
Hydrothermal Synthesis of Nano-Crystalline Hydroxyapatite
p.247
Caries Inhibitory Activity of the Nano-HA In Vitro
p.251
Structural Properties of Hydroxyapatite With Particle Size Less Than 10 Nanometers
p.255
Sintering Behaviour of Nanosized HAP Powder
p.259
Preparation of Nano-Sized Strontium Containing Tricalcium Phosphate Particles
p.263
Remineralization Effect of the Nano-HA Toothpaste on Artificial Caries
p.267

Caries Inhibitory Activity of the Nano-HA In Vitro

Article Preview

Abstract:

The purpose of this study is to examine the inhibitory effects of nano-HA on the caries-inducing properties of a four-organism bacterial consortium in vitro. A series of in vitro anticarious experiments have been carried out by using a continuous culture system. Streptococcus mutans, Streptococcus sanguis, Actinomyces viscosus, Lactobacillus rhamnosus have been chosen as the experimental bacteria. After 48 hours, the dental plaque surface structure is observed with the scan electron microscope and the bacterial colonization was evaluated on dental plaque. The results show that Spherical nano-HA and mixed nano-HA are proved to be effective in anticarious experiments, and especially spherical nano-HA is more striking. It is able to damage the formation of biofilms (dental plaque), postpone or end the process of acid generation of bacteria metabolism. After 7 days, the demineralization of the enamel has been detected by using TEM. The spherical nano-HA might have a remineralization to early caries to prevent and decrease caries.

You might also be interested in these eBooks
Bioceramics 19 View Preview

Info:

Periodical:

Key Engineering Materials (Volumes 330-332)

Pages:

251-254

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.330-332.251

Citation:

Cite this paper

Online since:

February 2007

Authors:

Xiang Cai Meng, Kui Long Lv, Jiu Xing Zhang, Da Li Qu

Keywords:

Caries, Continuous Culture System, Inhibitory Activity, Nanohydroxyapatite (HA)

Export:

RIS, BibTeX

Price:

Permissions CCC:

Request Permissions

Permissions PLS:

Request Permissions

Сopyright:

© 2007 Trans Tech Publications Ltd. All Rights Reserved

Share:

Citation:

References

[1] T. Koga, T. Oho, Y. Shimazaki and Y. Nakano: Vaccine 20(2002), p. (2027).

Google Scholar

[2] J. W. Costerton, Philip S. Stewart and E. P. Greenberg: Science Vol. 284 (1999), p.1318.

Google Scholar

[3] C.H. Sissons, T.W. Cutress, M.P. Hoffman and J.S.J. Wakefield: J. Dental Res. Vol. 70 (1991), p.1409.

Google Scholar

[4] X. Mneg, X. Li, and K. Lu: Materials Science Forum Vol. 475-479 (2005), p.2423.

Google Scholar

[5] T. J. Webster, C. Ergun, R.H. Doremus, R.W. Siegel and R. Bizios: Biomaterials Vol. 22(2001), p.1327.

Google Scholar

[6] R.J. Gibbons: J. Dent. Res. Vol. 63 (1984), p.378.

Google Scholar

[7] E. Newbrun: Science Vol. 217 (1982), p.418.

Google Scholar

[8] C. Sansone, J. Van Houte, K. Joshipura, R. Kent, and H.C. Margolis: J. Dent. Res. Vol. 72 (1993), p.508.

Google Scholar

[9] S.O. Akintoye, M. Dasso, D.I. Hay, N. Ganeshkumar and A.I. Spielman: Archives of Oral Biology 47 (2002), p.337.

DOI: 10.1016/s0003-9969(02)00020-1

Google Scholar