A Window of Opportunity: Designing Carbon Nanomaterials for Environmental Safety and Health

Article Preview

Abstract:

Carbon nanomaterials are among the best known and most promising products of the nanotechnology movement. Some early studies suggest that fullerenes and nanotubes may pose significant health risks, and this has given rise to an emerging literature on carbon nanotoxicology. This young field has now begun to yield insight into toxicity mechanisms and the specific material features involved in those mechanisms. This paper explores the potential to alter those material features through post-processing or reformulation with the goal of reducing or eliminating carbon nanomaterial health risks. The paper emphasizes the important roles of metal content and bioavailability, carbon surface chemistry, and nanomaterial aggregation state. The nanotechnology movement has been given a unique "window of opportunity" to systematically investigate the toxicity of nanotechnology products and to develop ways to manage health risks before large scale manufacturing becomes widespread.

You might also be interested in these eBooks

Info:

[1] S.K. Smart, A.I., Cassady, G.Q. Lu, and D.J. Martin, Carbon 44 (2006) p.1034.

Google Scholar

[2] R. Hurt, M. Monthioux A. Kane, Carbon 2006 44 1028-1033.

Google Scholar

[3] A. Huczko, H. Lange, E. Calko, H., Grubek-Jaworska, P. Droszcz, Full. Sci Tech 9 (2001), p.251.

Google Scholar

[4] C. Lam, J.T. James, R. McCluskey, R. Hunter, Toxicol Sci 77 (2004) p.126.

Google Scholar

[5] D. Cui, F. Tian, C.S. Ozkan, M., Wang, H., Gao, Toxicol Lett 155 (2005) p.73.

Google Scholar

[6] N.W.S. Kam, T.C. Jessop, P.A. Wender, and H. Dai, J Am Chem Soc 126, (2004) p.6850.

Google Scholar

[7] E. Oberdörster, Environ Health Perspect, 112 (2004) p.1058.

Google Scholar

[8] C.M. Sayes, J.D. Fortner, W. Guo, D. Lyon, A.M. Boyd, K. D. Ausman, Y.J. Tao, B. Sitharaman, L.J. Wilson, J.B. Hughes, J.L. West, V.L. Colvin, Nano Letters, 4 (2004) p.1881.

DOI: 10.1021/nl0489586

Google Scholar

[9] J. L. Fortner, DY, C. M. Sayes, A. M. Boyd, J. Falkner, E. Hotze, L. Alemany, Y. Tao, K. Ausman, V. Colvin and J. Hughes, Environ Sci. Technol 39 (2005) P. 4307.

DOI: 10.1021/es048099n

Google Scholar

[10] E. Oberdörster, S. Zhu, T M. Blickley, P. McClellan-Green, M.L. Haasch, Carbon 44 (2006) p.1112.

DOI: 10.1016/j.carbon.2005.11.008

Google Scholar

[11] A.R. Oller, M. Costa, G. Oberdorster, Tox. Appl. Pharmacol. 143 (1997) p.152.

Google Scholar

[12] M. Costa and H.H. Mollenhauer, Science, 209 (1980) p.515.

Google Scholar

[13] E.T. Snow and M. Costa, Environmental and Occupational medicine; Lippincott-Raven Publishers: Philadelphia Chapt 75 p.1057 (1998).

Google Scholar

[14] Q. Zhang T. Kusaka, K. Sato Y. Mo, M. Fukuda, K. Donaldson, J. Occup. Health 40 (1998) 171.

Google Scholar

[15] F. Tao, B. Gonzalez-Flecha, L. Kobzik, Free Rad. Biol. & Med. 35 (2003) p.327.

Google Scholar

[16] J.A. Hardy and A.E. Aust, Chem. Rev. 95 (1995) p.97.

Google Scholar

[17] A.A. Shvedova, et al. J. Toxicol. Environ. Health., Part A 66 (2003) p. (1909).

Google Scholar

[18] K. Donaldson, R. Aitken, L. Tran, V. Stone, R. Duffin, G. Forrest, A. Alexander Toxicol. Sci. 91 (2006) p.5.

Google Scholar

[19] B. Fubini and C.O. Areán, Chem. Soc. Rev. 28 (1999) p.373.

Google Scholar

[20] A. Shukla, et al. Free Rad. Biol. & Med. 34 (2003) p.1117.

Google Scholar

[21] S. Hirano, N. Kodama, K. Shibata, K.T. Suzuki, Toxicol. Appl. Pharmacology, 104 (1990) p.301.

Google Scholar

[22] K. Marubashi, S. Hirano, Suzuki K.T., Toxicology Letters, 99 (1998) 43.

Google Scholar

[23] Y. Nakamura, Y. Tsumura, Y. Tonogai, T. Shibata, Y. Ito, Fund. Appl. Toxicology 37 (1997) 106.

Google Scholar

[24] D. Schubert, R. Dargusch, J. Raitano, S-W. Chan, Biochem. Biophys. Res. Comm. 342 (2006) 86.

Google Scholar

[25] J.L. Domingo, Toxicology and Environmental Health, 42 (1994) p.123.

Google Scholar

[26] D.F. Lison, Chapter 73 in Environmental and Occupational Medicine, Third Edition (W.N. Rom, Ed. ), Lippincott-Raven, Philadelphia, (1998).

Google Scholar

[27] N. Lombaert, M. De Boeck, I. Decordier, E. Cundari,. D. Lison,. M. Kirsh-Volders, Toxicology Letters 154 (2004) p.23.

DOI: 10.1016/j.toxlet.2004.06.009

Google Scholar

[28] Q. Zhang, Y. Kusaka, K. Sato, J. Toxicology Envir. Health Part A 53 (1998) 423.

Google Scholar

[29] K. Jian, I. Kulaots, A. Yan, G.P. Crawford, R.H. Hurt, Carbon, 44 (2006) 2102.

Google Scholar

[30] A. Yan, X. Cheng, I. Kulaots, B.W. Sheldon, R.H. Hurt, Controlling water contact angle on carbon surfaces from 5 to 167 degrees, Carbon, in press, (2006).

DOI: 10.1016/j.carbon.2006.08.004

Google Scholar

[31] H. Dumortier, S. Lacotte, G. Pastorin, R. Marega, W. Wu, D. Bonifazi, J. Briand, M. Prato, S. Muller, A. Bianco, Nano Letters 6 (2006) 1522-1528.

DOI: 10.1021/nl061160x

Google Scholar