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Preparation of Vaterite/Poly(lactic acid) Composites with Excellent Apatite-Forming Ability

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Abstract:

A new type of ceramic-polymer biomaterial having excellent apatite-forming ability in simulated body fluid (SBF) was prepared by hot-pressing a mixture consisting of poly(-L-lactic acid)(PLA) and calcium carbonate (vaterite). The composite containing 30% vaterite showed no brittle fracture behavior and comparably high bending strength of ~50 MPa. Apatite layer of several micrometers in thickness formed on its surface after soaking in SBF at 37°C only for 1 day. Osteoclast culture tests showed that the composite coated with apatite has excellent bioresorbability. After incubation of human osteoblasts, mineralized bone nodule formation was seen on the surface.

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Periodical:

Key Engineering Materials (Volumes 284-286)

Pages:

449-452

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.284-286.449

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Online since:

April 2005

Authors:

Toshihiro Kasuga, Hirotaka Maeda, G. Jell, Ioan Notingher, Larry L. Hench

Keywords:

Apatite Formation, Biomineralization, Calcium Carbonate, Composite, Poly(lactic acid) (PLA)

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© 2005 Trans Tech Publications Ltd. All Rights Reserved

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