The paper is aimed at conducting a developmental and practical research on “life skill” cultivation in P.E. curriculum system of universities. In the research, 302 freshmen (137 male students and 165 female students) from College of Education and College of Humanities at Hunan University of Science and Technology were randomly selected to be the research targets. All selected students were then divided randomly into the experimental group and the contrast group, with 153 students in the experimental group and 149 students in the contrast group. These students were arranged to go through physical education experiment designed for improving teen-agers’ life skills. Document literature, mathematical statistics, Likert-type scales and other methods were put into use in the research to test students’ knowledge and confidence in life skills for subsequent assessment. The experimental result has shown that, students in the experimental group were observably improved (P<0.05) 1 in one aspect of both life skill test and confidence test.