Manufacturing enterprises are now facing serious challenges and pressures from the tide of globalization. After analyzing the features of process preparation resource, the integration service mode and semantic description for process preparation based on manufacturing grid is studied. Firstly, process preparation resources are defined and classified. Secondly, information modeling of process preparation in manufacturing grid is discussed. Thirdly, the integrated service mode of process preparation resources in manufacturing grid is discussed. Finally, an example of one kind of process preparation resource is given to illustrate the resource semantic description based on XML. Above research is benefit for application of manufacturing grid and the information progress of national defense industry.