The Pro/Toolkit secondary development tools and Visual C++ programming language are used in the second development of the Pro/E, which can realize the parametric design of machine tool’s parts. Input the parameters, the system will automatically generate 3D models. This system can reduce the time of machine tool design and development, and improve the design efficiency. The information management module system can realize the management of machine tool important design parameters, which greatly lightened designers’ workload. This paper develops the parameterization design of supporting stand for the example, and introduces this development mentality and its key technologies in detail.