Design of a pharmaceutical industry management system based on ERP and CRM integration, including design background, function and implement, are presented in this paper. The designed system applies middleware technology in data exchange between ERP and CRM, and all the data is transferred in XML format. The mainly integrated function modules are customer management module, product information module and sales module. Snowflake mode is used in data warehouse to eliminate data redundancy and to save storage space. The system can improve management ability and competition superiority of the pharmaceutical industry through ERP and CRM integration.