Tailor rolled blanks (TRB) is made by flexible rolling system. And the thickness of TRB can be determined according to the load of this section. With its good bearing capacity and designed, it can be used to make automotive body for reducing the material and lower the weight. This paper describes the rolling process of TRB, and rolling simulation model of TRB was constructed using Deform-3D. The result curve of TRB rolling simulation was compared with a given target curve to determine the TRB rolling implementation, and had a simple analysis about the factors of each cross section during rolling. This research will give a guidance to realize the rolling of TRB.