Throughout history till today, earthquake prevention and disaster mitigation has been the eternal subject in engineering field. Security is the very premise for the subsistence and development of human beings. Entrusted with government correlation department, the examination of seismic safety and structural health diagnosis will be done in relation to the type, characteristic feature and damage, etc. of current masonry structure in Minnan District, which is in the spirit of “Emphasis on hedge against disaster relief”. According to current criteria as well as considering the actual situation of construction, various constructions will be evaluated scientifically by the on-the-spot survey, investigation, evaluation and analysis, from which get the various morbid state and principle of constructions in concordance with the differences of severity. On the other hand, in line with “rescuing” principle in order of importance and urgency, corresponding classification of disaster prevention and certain applicable and practical disposal ideas will be put forward in order to provide references for engineering practice and application as well as management and policy making for relevant department.