According to the extensive application of shield tunnel, large-diameter shield tunnel in particular, structure stiffness of shield tunnels varies in a large rang. In this paper, shield tunnels with different diameters and thicknesses are analyzed and calculated by time-history method. Stiffness ratio is identified to measure the relationship of structure’s stiffness and soil’s stiffness. The results indicate that dynamic moment and shear forces of shield tunnels have positive correlation with the stiffness ratio. Axial forces have positive correlation with thickness and diameter of lining structure.