As the capacity and water head of large hydropower projects become higher and higher, the flow-induced structural vibration of powerhouse becomes a very important problem for the design and operation process. Especially as the water head and the running speed are much higher for the pump-turbine than the general turbine, the hydraulic exciting vibration is very remarkable. In this paper the simulation results of free-vibration characteristics of powerhouse structure for different types were concluded and the frequency behavior of the pressure fluctuation in spiral case and draft tube were discussed. The structural dynamic responses under hydraulic exciting were presented including the dynamic responses of displacement, velocity, acceleration and stresses. Based on the vibration criterion of the powerhouse structure, the vibration evaluation was made.