This paper is focused on the evaluation of the structural influencing coefficient in multi-story moment-resisting steel frames involving local bucking effect, with due consideration to both their ductility and overstrength. Ductility and overstrength play an important role in keeping satisfactory performance of structures during strong earthquake. Firstly, moment-resisting steel frames of are designed according to Chinese seismic code. Based on the non-linear shell element method, both inelastic time history and pushover analyses has been performed on these steel frames to get the global capacity envelopes. The results show that number of stores and spans have effect on the behaviour factor values, and that the local buckling affects the ductility capacity of steel frames. Finally, based on the findings presented in the article, tentative influencing coefficient values are proposed for moment-resisting steel frames.