Paper Title:
Lysicamine in a Lotus Leaves Extract May Be Responsible for Antibacterial and Anti-Inflammation Activity
  Abstract

In the course of a search for chemotherapeutic agents inhibiting suspected peridontitis bacteria, extracted and purified substances from lotus leaf were identified by antimicrobial and Anti-inflammation activity tests with use of the broth micro-dilution methods on 96-microwell plate and ELISA assay. The antimicrobial activity of extracts was tested against four microorganisms, namely: Streptococcus mutans , Porphyromonas gingivalis, Actinobacillus actinomycetemcomitans and Candida albicans. The Anti-inflammation activity of extracts was tested for inhibition of inflammatory cytokines IL-8 and IL-6 in macrophage BF24. And one pure component was subjected to spectroscopic analysis using UV, IR, EMI-MS, EIMS, 1H-NMR, 13C-NMR, 1H-COSY and HMQC. Our data showed that the minimum inhibitory concentrations of the pour component was less than 5mg/ml for all four microorganisms and the minimum concentration with anti-inflammation was 0.2mg/ml for both IL-8 and IL-6. The component was determined to be Lysicamine. Thus, we conclude that Lysicamine extracted from lotus leaves may be a potential antibacterial and Anti-inflammation agent for oral infection .

  Info
Periodical
Chapter
Chapter 2:Materials Science and Bioengineering
Edited by
Barry Tan
Pages
189-193
DOI
10.4028/www.scientific.net/AMM.108.189
Citation
P. Wang, M. Z. Zhu, W. Huang, C. F. Huang, S. Wilson, "Lysicamine in a Lotus Leaves Extract May Be Responsible for Antibacterial and Anti-Inflammation Activity", Applied Mechanics and Materials, Vol. 108, pp. 189-193, 2012
Online since
October 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Byung Won Kang, T. Yoshida, Jong Baek Lee, S.J. Jeon, H.D. Choi
Abstract:In order to elucidate the relationship between the structure and biological activity such as anti-HIV and blood anticoagulant activity,...
721
Authors: Li Xin Huang
Textile Materials
Abstract:Cotton fabrics is treated for bacterial repellency and crease resistance with different kinds of chitosans. Through the study and test of the...
2693
Authors: Monica Monea, Mihai Pop, Alexandra Stoica, Teodora Ștefănescu
Chapter 4: Practice of Preclinical Studies of Materials and Technologies
Abstract:Early carious lesions induce odontoblast stimulation in tertiary dentine formation even before the lesion reaches the dentine. The most used...
260