In this paper, a numerical model is developed to simulate single droplet heat and mass transfer in a two-pieces solution with a saturated solvent vapor environment. Finite volume method and transient SIMPLEC algorithm in spherical coordinates system used for simulation. For simulation of the mass transfer, dimensionless equations of motion, heat transfer and mass transfer (based on mass ratio) are solved simultaneously. All the thermodynamic and transitional solution properties have been considered as a function of temperature and concentration. Verification of method is done by compare these numerical results with analytical and numerical analysis of other studies. Evaporation, absorption and condensation contours in a water droplet at uniform temperature at superheated water vapor and Distribution of Droplet's Surface Temperature, Constant Temperature and concentration lines as the modeling results are presented. The results are shown that 0.5% increase of concentration of droplet cause increase 8 degree C of mean temperature of droplet.