Erosion wear experiments on Nickel-Chromium cast iron were tested by MCF-30 erosion test machine. The structure and surface morphology of these samples were analyzed by Scanning Electron Microscopy (SEM), Transmission Electron Microscope (TEM) and XRD. The influences of the impact angle and acidity on erosion wear property were analyzed. The discipline of the erosion wear property was discussed as well. The experimental results indicate that after oil quench at 960°C and temper at 250°C, the alloy carbide (Fe, Cr)3C which works as the wear resistance skeleton distributes uniformly in the matrix ; the shape of erosion wear curve is “M”. and the biggest wear loss is when the impact angle is 60°; the erosion wear property is affected greatly by the strong acid, but is little even can be ignored when pH≥3. The erosion wear mechanism of Nickel-Chromium cast iron is selective wear.