Microcantilever hotplates use the self-heating phenomenon to achieve the required large, uniform temperature field or the cantilever-tip movement. The present study investigates the effect of self-heating on temperature and its distribution in microcantilever hotplates in monolith and u-shape configuration with different substrate materials, operating environments and applied voltages. The cantilevers are made of Si and SiO2 with a p-type Si resistor embedded. The cantilevers are operated in air and water at different applied voltages. The numerical analysis uses finite element analysis software ANSYS Multiphysics. Results show that monolith and u-shape cantilevers have similar temperature distributions, but the maximum temperature values in u-shape cantilever are higher.