Paper Title:
Investigation on Local Optical Parameters of Liver Tumors in Laser-Induced Thermotherapy
  Abstract

The method to investigation the changes of optical properties and evaluating the effect of laser application in real time is presented in this paper. In vivo measurements of the reduced scattering coefficient (μ’s) and tissue temperature (T) were performed with a functional near infrared spectroscopy (fNIRS) system and a temperature measurement system during LITT. Mice liver tumors were examined in vivo in different laser doses (0.8W, 1.0W, 1.2W, 1.4W) at a certain heating time (600s). The results showed that there were the same rising tendencies of the reduced scattering coefficient and temperature during LITT. They increased quickly at the beginning, gradually reached a stable state, and rose faster when the laser power was greater. When the tissue temperature was in the range of 50°C to 70°C, there was a clear linear relationship between μ’s and T. The linear equation was obtained for the first time.

  Info
Periodical
Chapter
Chapter 7: Computer Application in Design and Manufacturing (1)
Edited by
Dongye Sun, Wen-Pei Sung and Ran Chen
Pages
3998-4002
DOI
10.4028/www.scientific.net/AMM.121-126.3998
Citation
L. J. Dai, G. R. Hua, A. P. Qian, Z. Y. Qian, "Investigation on Local Optical Parameters of Liver Tumors in Laser-Induced Thermotherapy", Applied Mechanics and Materials, Vols. 121-126, pp. 3998-4002, 2012
Online since
October 2011
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$32.00
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