Modern CNC system adopts the NURBS interpolation for the purpose of achieving high-speed and high accuracy performance. However, in conventional control architectures, the computation of the basis functions of a NURBS curve is very time consuming due to serial computing constraints. In this paper, a novel multiprocessor-based motion controller on chip utilizing its high-speed parallel computing power is proposed to realize the NURBS interpolation. The motion control algorithm and I/O control are also embedded in the chip to implement real-time control and NURBS interpolation simultaneously. The experimental tests using an X-Y table verify the outstanding computation performance of the multiprocessor-based motion controller on chip. The result indicates that shorter sampling time (0.1 ms) can be achieved for NURBS interpolation and high-accuracy motion control.