Paper Title:
Synthesis and Performance of Molecular Imprinted Polymers as Drug Release Controller
  Abstract

Molecular imprinted polymers were synthesized using α-methylacrylacid as monomer, acetylsalicylic acid as template. Polyethylene glycol dimethylacrylate was taken as cross-linker. UV-Vis spectrophotometer was used to detect the drug-loading and releasing performances of these polymers. The studies showed that the imprinted polymers could load more drugs than non-imprinted polymer, and exhibited a slower drug-releasing rate than the latter at pH 7.4. The content of cross-linker had influences on drug-loading amounts. The imprinted polymer released few drugs at the buffer solution of pH 1.2.

  Info
Periodical
Edited by
Han Zhao
Pages
446-449
DOI
10.4028/www.scientific.net/AMM.130-134.446
Citation
H. J. Chu, H. L. Wei, J. Zhu, C. P. Nong, "Synthesis and Performance of Molecular Imprinted Polymers as Drug Release Controller", Applied Mechanics and Materials, Vols. 130-134, pp. 446-449, 2012
Online since
October 2011
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