The pressure resonance problem impelled by hydraulic pulsation power in piping networks is studied in this thesis. Through theoretical analyzing and computer simulating to the flow variation of multi-pulse sources accumulation, two concepts: the variable initial angle by equal probability and flow pulsation rare, are introduced. Some useful conclusions are also obtained. Most of piping networks vibration in engineering is aroused by the medium pressure pulsation. Destructive violent vibration is set off by the simulation of pressure pulsation when resonant occurred. In order to reduce the vibration, it is important to restrain pressure pulsation and to avoid the resonance areas determined by piping networks construction. On the basis of the optimized approximate model to meet the need of the practical engineering and fluidic network theory, this thesis is mainly concerned with the natural frequency of internal liquid vibration in pipelines. In this thesis a no-damping piping mathematics model as well as the transfer matrix method is employed, and the computer simulation is used in theoretical researching. The simulation software of pressure fluctuation for the complex fluidic transmission systems is developed. The effects of every structure parameters of simulated hydraulic pipelines on the pressure pulsation performance are analyzed in details by using the software which makes us modify some structure parameters efficiently so as to optimize structure, evade resonant, reduce the amplitude of pressure pulsation and avoid fluid resonance. The experiments verify the conclusion of the computer simulation and show that the software is easy to be widely used in the dynamic optimum design of fluid transmission systems.