In order to improve the experimental evidence of hotoinitiator, the effects of various dose of photoinitiator on mechanical properties of nanohydroxyapatite composite were investigated. According to the light initiating system, CQ and DMAEMA accounted for 0.8wt％, 1.0wt％, 1.2wt％ of total resin matrix, respectively. And then NHA processed by KH-570 was mixed with resin matrix in the ratio of 55:45. Then three groups （A, B, and C） of light-cured nanohydroxyapatite composites were prepared. Karuisima composite resin was used as control group D. The cured depth, compressive strength, and flexural strength were determined in each group. The results showed that as the ratio of photoinitiator increased, the cured depth increased, while the mechanical function declined. In group B, there were no significant differences in compressive strength, and flexural strength as compared with control group, P>0.05. It is suggested that the quantity of CQ and DMAEMA in resin matrix were 1.0wt% respectively, the new light-cured nanohydroxyapatite composite has good qualities in both cured depth and mechanical property.