Paper Title:
Production of a Fibrinolytic Enzyme from Coprinus comatus YY-20
  Abstract

A strong fibrin-specific fibrinolytic enzyme was produced by liquid culture of Coprinus comatus YY-20. Soybean cake powder and sucrose as substrates resulted in the highest fibrinolytic activity. The optimal temperature for the production of the enzyme was found to be 21-25°C in the optimal medium (Soybean cake powder 50 g/L, sucrose 20 g/L). The optimal initial pH of the medium was found to be at the range of 5-8. The maximum fibrinolytic activity was observed at the stationary phase of cell growth. These results suggest that the culture liquid of Coprinus comatus YY-20 has potential as a source of physiologically active fibrinolytic enzymes.

  Info
Periodical
Chapter
Chapter 3: Chemical and Biomedical Engineering
Edited by
Honghua Tan
Pages
1195-1201
DOI
10.4028/www.scientific.net/AMM.138-139.1195
Citation
X. L. Liu, X. Q. Zheng, J. K. Zhang, "Production of a Fibrinolytic Enzyme from Coprinus comatus YY-20", Applied Mechanics and Materials, Vols. 138-139, pp. 1195-1201, 2012
Online since
November 2011
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Price
$32.00
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