The Preparation and Evaluation of the Combined Artificial Bone
| Periodical | Applied Mechanics and Materials (Volume 140) |
|---|---|
| Main Theme | Medical Materials and Engineering |
| Edited by | Robert Zhu |
| Pages | 1-6 |
| DOI | 10.4028/www.scientific.net/AMM.140.1 |
| Citation | Ke Ya Mao et al., 2011, Applied Mechanics and Materials, 140, 1 |
| Online since | November, 2011 |
| Authors | Ke Ya Mao, Fei Hu Zhou, Fu Zai Cui, Jiang Tao Li, Zi Shen Cheng, Peng Li, Zheng Wang, Ke Zheng Mao, Yang Wang |
| Keywords | Combined Artificial Bone, Self-Setting, α-Calcium Sulphate Hemihydrate, β-Tricalcium Phosphate |
| Price | US$ 28,- |
Every year, roughly two million patients worldwide sustain a bone grafting procedure to repair bone defects stemming from tumor, the wound, the infection, as well as other reasons [1, 2]. The bone transplantation is one of main methods to treat bone damages [3]. The gold standard is to use autologous bone or autograft [4]. However, both the need of the second surgery and morbidity at the extraction site [5-7] has been an incentive to search for alternative treatment. One of them is to form bone graft bone. Many materials have been widely chosen to form bone graft substitutes: metals, polymers, ceramics, dehydrate, and calcium phosphates [8-13]. Although these synthetic materials provide an immediate solution for many patients, their long-term performance is generally not satisfactory. This is often due to a mechanical property mismatch between the implant failure and tissue damage [14, 15]. The development of combined artificial bone with improved mechanical properties and enhanced biocompatibility calls for a biomimetic approach using natural bone as a guide.
