Objective：The aim of the study was to explore most effective way to control infection during implant treatment. Methods: The study was carried out in two implant operating surgeries (Surgery A, Surgery B), which were set up air disinfectant machine and ultraviolet disinfection respectively. For baseline measurements, the number of bacterials in the air of the two surgeries was counted at 5min, 15min, 30min, 45min and 60min before sanitizing. To compare sanitizing effect of static air disinfection, air samples from these surgeries were collected for bacterial cultivation after sanitizing for 5min, 15min, 30min, 45min and 60min, and the the sterilization rate was calculated. To compare dynamic air disinfection, the two surgeries were sterilized before implant surgery, and the air samples were collected at 5min, 15min, 30min, 45min, 60min after implant operation. Results: There were no significant differences between air disinfectant machine and ultraviolet disinfection in static air disinfection (p<0.05). However, air disinfectant machine was more effective in dynamic air disinfection. Conclusion：Air disinfectant machine is the most effective way for the prevention of nosocomial infections.