The steel-concrete hybrid structure is a new special industrial structure in large thermal power plants. It is composed of a spatial steel truss and steel-concrete tubular columns. Its stiffness and mass is highly non-uniform at vertical direction. Its temperature effect is obvious because its steel truss is a high order statically indeterminate structure. Types and characteristics of temperature load prescribed in codes are introduced. Temperature effect of the steel-concrete hybrid structure is calculated by FEM analysis software SAP2000 in four different supporting blocks. The structural internal force and distortion under temperature effect is analyzed. The influence of supporting blocks on the structual temperature effect is analyzed. The structural supporting block form to advantageously release its temperature effect is presented. Some advice is presented based on the analysis results.