In cutting experiment, high alloy antifriction cast irons were selected. Through high-speed cutting experimentation, the materials’ performance and requirement for tools were analyzed. The feasible cutting capacity and tool parameters were ascertained. The cutting defect and solving method were discussed. The results indicate that there are high hardness, high wear resistance and brittleness of high alloy antifriction cast irons. In ensuring the technical requirements of work-piece machining, PCBN is a better tool material. When the tool orthogonal rake angle =-6°, the tool’s durability is higher and machining quality is better. High cutting efficiency can be obtained, when cutting speed vc is from 75 to 100 m/min, the feedrate f is less than 8 mm/min, and the cutting depth ap is from 0.1 to 0.3 mm. These cutting dosages are appropriate in machining high alloy antifriction cast irons.