Paper Title:
Correlation of Optical Properties and Temperature Distribution in Laser-Induced Thermotherapy of Porcine Liver Tissue
  Abstract

Laser induced thermotherapy (LITT) is a promising local treatment for irresectable liver tumors. For evaluating the effect of laser application in real time and ensuring the optimal effect in LITT, exploration the changes of optical properties and temperature distribution in tissue, and their correlation are indispensable. In vivo measurements of the reduced scattering coefficient (μ’s) and tissue temperature (T) were performed with a functional near infrared spectroscopy (fNIRS) system and a temperature measurement system during LITT. Fresh porcine liver tissue samples in vitro were examined in different laser doses (0.95W, 1.23W, 1.42W) and at a certain heating time (600s). There were the same rising tendencies of the reduced scattering coefficient and temperature during LITT. They increased quickly at the beginning, gradually reached a stable state, and they rose faster when the laser power was greater. When the tissue temperature was below 50°C or above 65°C, there was only a slight increasing of μ’s .When the tissue temperature in the range of 50°C to 65°C, μ’s changed more obviously, and there was a clear linear relationship between μ’s and tissue temperature. The linear equation was obtained for the first time. These results can effectively guide the study of evaluating the effect in real time during LITT.

  Info
Periodical
Edited by
Long Chen, Yongkang Zhang, Aixing Feng, Zhenying Xu, Boquan Li and Han Shen
Pages
769-772
DOI
10.4028/www.scientific.net/AMM.43.769
Citation
A. P. Qian, G. R. Hua, H. Zhang, Z. Y. Qian, "Correlation of Optical Properties and Temperature Distribution in Laser-Induced Thermotherapy of Porcine Liver Tissue", Applied Mechanics and Materials, Vol. 43, pp. 769-772, 2011
Online since
December 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: De Gong Chang, Xue Feng Wang, Fu Qin Yang, Jiang Zhong Wang
Abstract:The effects of the lubricant properties on the lubricating performance of the tripod sliding universal joint were studied under thermal...
302
Authors: Shen Cheng, Feng Zhong Sun, Ming Gao
Abstract:In order to find an excellent kind of heat transfer element under vacuum condition, the heat transfer performance of tube bundles of...
2224
Authors: B.J. Xiao, Cheng Yong Wang, Ying Ning Hu, Yue Xian Song
Abstract:A two-dimensional orthogonal thermal-mechanical finite element model by Deform2D finite element analysis software is established in the...
590
Authors: Jie Jiang, Dang Sheng Xiong, Jian Liang Li, Yan Shi
Abstract:Components of space machines often works at high temperature and vacuum, or on other rigour conditions, the traditional liquid lubricant...
706
Authors: Xiao Hong Zhang, Jiang Tao Zhang
Chapter 6: Materials Engineering
Abstract:According to two parameters combination of the material thickness and air-gap depth, from the angle of pure optimization, this paper obtained...
1187