The bracket-cable is one of the important structures of transmission control system of Heavy Commercial Vehicle. By using the compliance (strain energy) as an object function and the volume as constrain, the topology optimization design for the bracket-cable is performed with Hyperworks10.0, which is made considering the characteristics of structure, constraints and forces etc. To meet the structural strength and stiffness requirements, 34.7% of the mass are decreased after the process. The generalization designing method of the structure of the bracket is also provided. The Structure analysis and the topology optimization based on the finite element method may help us get the best variation of the design during the developing phase. It has also significance to shorten the design process and to improve the product quality.