The supporting piles of deep foundation pits are usually made in reinforced concrete materials and rarely in prestressed concrete materials. But prestressed concrete materials have higher stiffness and less deformation and are suitable for controlling displacements or settlements. So, in this paper a practical engineering project as an example, the prestressed concrete supporting piles of the deep foundation pit are calculated and designed. Then, the settlement and inclination of the building adjacent the foundation pit with the prestressed concrete piles are calculated in the numerical software, FLAC. The results calculated in FLAC are compared with the actual settlement and inclination of the adjacent building during the foundation pit is excavated. The comparison confirms the feasibility of the supporting structure. This is a useful trial on the design of the prestressed concrete supporting piles.