In consistent with sustaining development, recycled aggregate concrete (RAC)that is made from recycled concrete aggregates could be a perfect solution to resource and environment preservation. It is a kind of practical and economic material to reuse the great amount of construction and demolition wastes, which has received many discussions nowadays. But, its fatigue behavior is different from other concretes as a result of different property of the aggregate of recycled concrete and other concrete. In order to apply RAC more effectively, it is necessary to study its properties especially for those aggregates from earthquake-stricken area for post-earthquake reconstruction. Therefore, on the basis of experimental research, the fatigue behaviors and microstructure of recycled concrete are studied in this paper. The present paper deals with investigations on fatigue behavior of the axial and eccentric compression performance of recycled aggregate reinforcement concrete specimens with contain recycled aggregate proportion of 0%、50%、100%. Then micro-structural observations of the specimens by means of scanning electron microscopy (SEM) were obtained. Based on the analysis of experiment results, it can be proved that it is feasible to apply recycled concrete to practical engineering.