The path of tire pattern’s impact on interior noise and vibration was analyzed. The same type tires with six kinds of different tread pattern were selected as the investigating subjects, and the interior measuring points’ vibration and noise signals of different tires were measured under full load condition. The basic theory of Wavelet Transform (WT) and its signal reconstruction principle were researched, and 1/3 octave Morlet wavelet was induced and analyzed. The vibration and noise signals of measuring points were transformed by using 1/3 octave Morlet wavelet, distribution features of vibration and noise signals of six tires with different tread pattern were made a comparison in time domain and frequency domain, and the distinct results of different tires were achieved. The advantage of WT in the aspect of time-frequency analysis for time domain signal is revealed.