Paper Title:
Platelet Adhesion on Silicon Modified Carbon Nanotubes Films
  Abstract

Owing to its high mechanical strength, chemical inertness, low frictional coefficient, high wear and corrosion resistance properties and so on, carbon nanotubes (CNTs) films have emerged as a potential material for biomedical applications. In order to investigate the blood compatibility properties of CNTs films synthesized on the silicon (Si) substrate using thermal chemical vapor deposition, the blood compatibility was evaluated in vitro by the platelet adhesion and the activated partial thromboplastin time (APTT). The experimental results demonstrated that the Si-CNTs films reduced thrombus formation by minimizing the platelet adhesion, activation , aggregation and had a tendency to retard the intrinsic coagulation activities of blood due to a higher APTT compared to Si, lower temperature isotropic pyrolytic carbon (LTIC) and Polydimethylsiloxane (PDMS) materials. Further, we found that hydrophobic surfaces are more prone to direct cellular motility in comparison with hydrophilic surfaces. It is concluded that CNTs films on the Si substrate were effective for improvement of blood compatibility.

  Info
Periodical
Edited by
Liang Gao
Pages
12-16
DOI
10.4028/www.scientific.net/AMM.69.12
Citation
G. Li, S. X. Zhu, "Platelet Adhesion on Silicon Modified Carbon Nanotubes Films", Applied Mechanics and Materials, Vol. 69, pp. 12-16, 2011
Online since
July 2011
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Akiyoshi Osaka, Tomohiko Yoshioka, Takeshi Yabuta, Kanji Tsuru, Satoshi Hayakawa
Abstract:Organic-inorganic hybrids involving Ti-O bonds were coated on stainless-steel (SUS316L)substrates. Tetraisopropoxide and titanium...
713
Authors: Feng Juan Jing, Lu Wang, Y.W. Liu, J.Y. Cheng, Yong Xiang Leng, R.K.Y. Fu, X.B. Zhao, Paul K. Chu, Nan Huang
Abstract:Cerium oxide films have been fabricated using dual plasma deposition. X-ray diffraction. (XRD) reveals a crystalline phase and X-ray...
749
Authors: Zhen Yi Shao, Ping Yang, Yong Xiang Leng, Qi Zhang, Guo Jiang Wan, Hong Sun, Guang Jun Cai, Nan Huang
Abstract:Si-N-O films have drawn researcher’s much attention recently due to their potential superiority in blood compatibility of biomaterials. In...
1407
  | Authors: Ming Zhou, Jia Hong Yang, Xia Ye, Ao Ran Zheng, Gang Li, Pei Fang Yang, Yi Zhu, Lan Cai
Abstract:Regular arrays of micro-pillars and nano-grooves structures on the silicon wafer are fabricated by using soft lithography, and the three...
129
Authors: Li Li Xue, Ping Long, Huan Wei, Ying Liang
Abstract:Hemocompatibility is a key property of biomaterials that come in contact with blood. Surface modification has shown great potential for...
600