This paper presents a nonlinear finite element (FE) analysis on the mechanic behavior of concrete filled steel tubular (CFST) composite frames. The main purpose of the FE analysis was to investigate the seismic behavior of composite frames. Three kinds of nonlinearity, namely material nonlinearity, contact nonlinearity and geometry nonlinearity, were taken into account in the FE model using MSC.Marc. The element type, connection between element, material constitutive law and boundary condition was described in detail. The elasto-plastic behavior, as well as fracture and post-fracture behavior, of the FE analysis models fitted well with those of the test specimens. The beam and panel zone deformation of the analysis models is also in good agreement with that of the test specimen. It is concluded that FE model of CFST composite frame is reliable and could be regarded as a helpful tool to expand the information on seismic behavior of CFST composite frame.