Aerobic composting is a method for sanitary disposal of human feces as has been used in bio-toilet systems which can be used at family in city to save water and to control water pollution. In this study, batch experiments were conducted using a closed aerobic composting reactor with sawdust as the bulky matrix to simulate the condition of a bio-toilet for sanitary disposal of human feces. Attention was paid to the biodegradation of organic matters under the thermophilic and mesophilic conditions. The results indicated that: more 70% removal of fecal organic matters(mainly in first 6-8 days) observed at 60°C while more 63% (mainly in first 10-11 days) at 35°C in a two-week composting period. Removal of organic matters of thermophilic conditions was more than that of mesophilic conditions with maturity period (at 60°C) shorter than that(at 35°C). The organic matter’s biochemical degradation of similar level 1 dynamics model can build. Using the experimental data of composting reaction, calculated out respectively reaction kinetics constants 0.4413(at 60°C) and0.2864(at 35°C), the former is as 1.65 times as the latter. It indicated that thermophilic composting could be considered to reach more than 70% fecal organic removal and shorten maturity period of compost.