The factors affecting the TBM tunnel behavior in jointed rock mass is investigated. In the numerical models the concrete segment lining of TBM tunnel is concerned, which is simulated as a tube neglecting the segment joint. And the TBM tunnel construction process is simulate considering the excavation and installing of the segment linings. Some cases are analyzed with different joint orientation, joint spacing, joint strength and tunnel depth. The results show that the shape and areas of loosing zones of the tunnel are influenced by the parameters of joint sets and in-situ stress significantly, such as dip angle, spacing, strength, and the in-situ stress statement. And the stress and deformation of the tunnel lining are influenced by the parameters of joint sets and in-situ stress, too.