Microseismic will produce when rock mass break. The occurrence of microseismic monitoring has close relationship to the energy release and crack's evolution in the rock mass. Therefore the microseismic monitoring can be used to predict the future rupture of the rock mass. MS location is the base of this prediction. The method of solving locating equation and the stability of answer are the key matter of microseismic monitoring applications in engineering fields. This paper uses Gauss-Newton iterative method to solve locating equation in order to advancing the precision and stability of answer and reducing the calculation workload. Based on the optimization toolbox of Matlab, the non-linear locating equations are solved and the visible locating results of microseismic are achieved.