Soil liquefaction is extremely detrimental to the Central Henan transit railway line project. The present study proposes a preliminary design to evaluate the effects of liquefaction and to determine the parameters and protective measures that need to be implemented. The geological properties, clay content, groundwater level, and the thickness of the overlying non-liquefied soil were initially determined. Then, a standard penetration test was employed to analyse the soil liquefaction potential in an iron mine in the Central Henan rail transport project. The evaluation of similar engineering project sites with middle-class areas vulnerable to liquefaction is important to determine the necessary anti-liquefaction measures.