The first task in health information system integration is to solve the problems of an “isolated information islands” and achieve the information and resource sharing. Some health information system integration technologies based on SOA and web services is researched. A prototype system of health information system integration based on SOA and web service is put forward. An integrated client, which employs the data redirection techniques in operating systems and is called the universal health information integration component, is developed. A real case study is used to show the design and implementation details as well as the valid integration among the heterogeneous system we have obtained.