The moderate pollution load of APMP effluents provides a chance for a new treatment process--combination of biological pre-treatment and coagulation treatment. Biological pre-treatment can reduce the pollution load and produce biomass at the same time. The removal of COD was 60.22% and the yield of biomass was 7.12g/L at the optimized conditions treated by Aspergillus niger. And the removal of acid-soluble lignin and color were up to 60% and 42.57%. The coagulation treatment was applied after bio-treatment by using alum and PAM as coagulation agent. The conditions of coagulation were optimized in this article. The optimized conditions were: Dosages of alum and PAM were 1000-1200mg/L and 2mg/L, pH is 5, stirring time is 30S at 300rpm, the temperature is 50°C. The coagulation removals of COD, color and turbidity were 83.80%, 86.38% and 98.33%. The removals of color were characterized by absorbance of 465nm, 325nm, 275nm and 254nm.