The research on multiaxial fatigue life prediction methods is reviewed in the present paper from two aspects of experiment and theory. It is pointed out that the reasonable methods of the critical plane determining, multiaxial cycle counting and multiaxial fatigue damage parameter fixing are necessary if the fatigue life prediction models established under the multiaxial constant amplitude loading were applied to the life prediction of the complex multiaxial load. The shortcomings of existing researches are discussed. In the aspect of experiment, it is devoid of the multiaxial fatigue test that the loading components acted with different frequencies, and in the aspect of theory, the additional hardening effect of the multiaxial out-of-frequency loading is not considered. Both in the theoretical research and practical engineering applications, the problem of the out-of-frequency multiaxial loading is a pressing issue.