It is difficult to fabricate one sensing element to simultaneously sense three linear acceleration components and three angular acceleration components, so as to find rare reports on six-axis accelerometer. The aim of this on-going project was to research an integrated six-axis accelerometer using parallel mechanism as the structure for sensing element. In order to optimize so many parameters, the paper defined the important static characteristic indices, analyzed the relationship between indices and structural parameters of sensing element. Based on the definition of the indices, the structural parameters were designed by the physical model of solution space. Finally, FEM simulation experiment is carried out to verify effectiveness of the method.