During the drilling of stacked materials, burrs forming on both the surface layer and the interlayer have some undesirable characters with regard to assembly quality, and deburring is a time-consuming and costly operation. This paper presented an experimental study on dry drilling of Ti-6Al-4V titanium alloy and 7075-T6 aluminium alloy stacked materials, which was performed by using uncoated cemented carbide drills. The burr size was evaluated at various spindle speeds, feed rates, stacking sequence and clamp force. Finally, the burr morphology was observed and analyzed. The best process parameters recorded in this paper were at the spindle speed of 2000r/min, the feed rate of 0.075mm/r, the pressure of 0.3MPa and the stacking sequence of the Ti-6Al-4V titanium alloy on top of the 7075-T6 aluminium alloy.