High pressure isolation plug train is a remote control, tetherless, highly piggable and high pressure isolation tool. The advantage of using the pressure isolation tool is to minimize production down time. Domestic research has started recently because of the foreign blockade of its core technologies, there are no relative products coming out currently. The smartplug that have been mentioned consist of plugging module, pigging module, hydraulic power module and communication and control module. The paper describes design ideas of each module in detail respectively and according to the design methods the prototype with diameter of 12 inches has been produced so far. Sealing pressure achieves 10Mpa by experiment. Looking forward to the technology would be applied in pipeline valve replacements and repairs, riser replacements and repairs, pressure test of risers and pipelines, midline pipeline repairs and relative engineering areas.