There are continuous high concerns on formation protection technology in international petroleum engineering field. The reservoir drill-in fluid (RDF) is the first non-native fluid to contact formation, and which influences directly the ultimate capacity of oil and gas well. The paper discusses the smart RDF design method based on conventional drilling fluid. The designed RDF system is characterized as good formation damage control, as well as the performance easily adjusted for field application. The technology combines ideal packing technology with active calcium carbonate to obtain low permeability filter cake, high return permeability and low initial flowing pressure. The sized calcium carbonates contribute to develop sealing zone for preventing filtrate and solids from invading into formation, and the organophilic passageway in filter cake (the active calcium carbonate) is favorable to open automatically passageway for oil and gas during production. Different modifiers used to ground calciumcarbonate surface modification are evaluated in laboratory. And the laboratory results show modified calcium carbonates are comfortable with conventional drilling fluids additives such as XC(Xanthan ), potassium polyacrylate(K-PAM), sodium carboxymethyl cellulose(Na-CMC).