Rotating fluids experiments were carried out by CAP2000+ cone viscometer, to examine the drag reduction properties of dimples arranged in quasicrystal structure. The dimples were fabricated on the surface of duralunmin (LY12) plates. Compared with the periodic arrays, the dimples arranged in quasicrystal structure, especially the 12-fold quasicrystal structure, could significantly reduce the wall shear stress. And the relative drag reduction efficiency changes periodically with the depth of dimple. Flow-visualization experiment verified that the coherent effect of dimples arranged in quasicrystal structure and the fluids could efficiently inhibit the extending intensity of radial secondary flow, which strengthens the drag reduction effect.