Paper Title:
Novel Antibacterial Nanofibers of Chitosan and Polyurethane Prepared by Electrospinning

The chitosan(CS)/polyurethane(PU) blend nanofibers have been prepared for the first time by electrospinning. Formic acid (FA) and Hexafluoroisopropanol (HFIP) were found to be the co-solvent for electrospinning. The CS/PU blend solutions in various ratios were studied for electrospinning into nanofibers. The diameter and morphology of the fibers were shown by scanning electron microscope (SEM). It was found that the average diameter of the chitosan/PU blend fibers became larger, and the morphology of the fibers became finer with the content of PU increasing. To show the molecular interactions, CS/PU fibers were characterized by Fourier transform infrared spectroscopy (FT-IR). Moreover, the antibaterial activity of blend nanofibers against Escherichia coil (E.coil) was measured via optical density method. The blend nanofibers exhibited satisfying antibacterial activity against E.coil, even the chitosan concentration was only 5wt%. Therefore, the spun nanofibers are expected to be used in the native extracellular matrix for tissue engineering.

Advanced Materials Research (Volumes 150 - 151)
Edited by
Jinglong Bu, Zhengyi Jiang and Sihai Jiao
Wei Min Kang et al., 2010, Advanced Materials Research, 150-151, 1452
Online since
October 2010
US$ 28,-
Authors: Xiao Liang Wang, Xu Dong Li, Xiao Min Wang, Jian Lu, Hui Chuan Zhao, Xing Dong Zhang, Zhong Wei Gu
Abstract:Collagen (Col) and chitosan (Chi) are both natural polymers and have received extensive investigation in recent years in the field of tissue...
Authors: Natthan Charernsriwilaiwat, Praneet Opanasopit, Theerasak Rojanarata, Tanasait Ngawhirunpat
Abstract:Electrospinning is a technique use to fabricate ultrafine fibers with diameters in the nanometer range. The electrospun fiber mats have high...
Authors: Sheng Hua Lv, Xiao Liang Yan, Rui Jun Gao
Chapter 3: Organic Polymer Materials
Abstract:The chitosan was degraded by hydrochloric acid and the effects of concentration of chitosan, amount of hydrochloric acid, reaction...
Authors: Ya Bo Fu, Dong Li Li, Wen Cai Xu, Xia Qing Tian
Chapter 1: Advanced Engineering Materials
Abstract:Gas permselective packaging film is an emerging material which enables it with gas selective permeation functions so as to keep the...
Authors: Jayachandran Venkatesan, Se Kwon Kim
Chapter 4: Ceramic Materials / Superconducting Materials
Abstract:In the recent years, significant developments have been achieved with chitosan and hydroxyapatite (HAp) scaffolds for bone tissue...