Paper Title:
Synthesis and Properties of N,N-Dimethyl-O-Quaternary Ammonium Chitosan
  Abstract

N,N-dimethyl-O-quaternary ammonium chitosan(NNQAC) was synthesized from chitosan by N-dimethylation then quaternized by 2,3-epoxy propyl trimethyl ammonium chloride. The structure of NNQAC was characterized by FTIR. Properties of quaternary ammonium chitosans, including solubility, antimicrobial activity, water-absorption and water-retention ability, were investigated. The results showed that NNQAC was water–soluble in neutral and basic environments. The moisture-absorption and retention abilities of NNQAC were higher than that of chitosan and equivalent to hyaluronic acid. The antibacterial activities of NNQAC were tested against Bacillus subtilis, Escherichia coli and Staphylococcus aureus. In water medium, NNQAC exhibited MIC values in the range of 10 to 2.5 μg/mL.

  Info
Periodical
Advanced Materials Research (Volumes 152-153)
Edited by
Zhengyi Jiang, Jingtao Han and Xianghua Liu
Pages
1337-1341
DOI
10.4028/www.scientific.net/AMR.152-153.1337
Citation
Z. L. Cao, W. W. Liu, J. J. Xiong, N. Qu, H. X. Li, G. W. Yao, "Synthesis and Properties of N,N-Dimethyl-O-Quaternary Ammonium Chitosan", Advanced Materials Research, Vols. 152-153, pp. 1337-1341, 2011
Online since
October 2010
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$32.00
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