Paper Title:
Supercritical Solvent Impregnation in Controlled-Release Drugs
  Abstract

In the field of pharmaceutical industry, the controlled-release drugs have received considerable attention in the last years. Impregnation using supercritical fluid technology has already proven its feasibility in the preparation of controlled release systems. The use of supercritical fluids such as supercritical CO2 has provided a ‘clean’ and effective alternative to traditional methods of drug releasing and polymer processes. In particular, scCO2 has a number of unique properties that make it possible to process both bioactive molecules and amorphous polymers without using toxic organic solvents or elevated temperatures. A high purity product, free of residual solvents is obtained, since no organic solvents are involved in the impregnation process. Here, we review the advantages of supercritical fluid and the preparation of controlled-release drugs by supercritical solvent impregnation.

  Info
Periodical
Advanced Materials Research (Volumes 152-153)
Edited by
Zhengyi Jiang, Jingtao Han and Xianghua Liu
Pages
1462-1465
DOI
10.4028/www.scientific.net/AMR.152-153.1462
Citation
Z. Tian, N. C. Bing, Y. Zhang, L. L. Wang, W. Qiao, "Supercritical Solvent Impregnation in Controlled-Release Drugs", Advanced Materials Research, Vols. 152-153, pp. 1462-1465, 2011
Online since
October 2010
Export
Price
$32.00
Share

In order to see related information, you need to Login.

In order to see related information, you need to Login.

Authors: Eric Blond, N. Schmitt, Olivier Arnould, François Hild, J. Poirier, P. Blumenfeld
1751
Authors: Tae Won Kim, Jung Teag Kim, Chan Young Park, Chang Hun Kim, Chang Sik Ju
Abstract:Supercritical impregnation of eicosane into polyester fiber was experimentally examined. Polyester fiber was bound on the cylindrical...
1095
Authors: Hullathy Subban Ganapathy, Min Hee Woo, Seong Soo Hong, Kwon Taek Lim
Abstract:Supercritical carbon dioxide (scCO2) was used as a processing medium for the fabrication of drug encapsulated poly(DL-lactide-co-glycolide)...
501
Authors: Li Min Li, San Kui Xu, Xiao Dong Wang, Nan Nan Guo, Yun Lai Su, Peng Zhang
Chapter 7: Biochemical Industry
Abstract:CuO/γ-Al2O3 catalysts were prepared by supercritical CO2 (SC-CO2) impregnation method. The preparation was carried out in SC-CO2 with...
1313